Chromosome Walkings

《英文msh词典》Chromosome Walkings
[入口词] Chromosome Walkings
[主题词] Chromosome Walking
[英文释义] A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome.